Akabori Amino Acid Reactions

1. Oxidize an alpha amino acid by heating with an oxidizing sugar.

2. Reduce alpha amino acids and esters by sodium amalgam and ethanolic HCl to alpha amino aldehydes.

S. Akabori, J. Chem. Soc. Japan, 52, 606(1931); Ber, 66, 143,151(1933); J. Chem. Soc. Japan, 64, 608(1943);

3. Form alkamines by heating aromatic aldehydes with amino acids. No reaction observed with teriary amino groups.

  • Example is pending
    •

    • E. Takagi, et al., J. Pharm. Soc. Japan, 71, 648(1951); 72,812(1952)
    A. Lawson, H.V. Motley, J. Chem. Soc., 1955, 1695
    A. Lawson, J. Chem. Soc. 1956, 307.


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